
Dr Mark Tarn
- Position: Research Fellow
- Email: M.D.Tarn@leeds.ac.uk
- Phone: +44(0)113 343 5605
- Location: 10.128 School of Earth and Environment
- Website: School of Physics and Astronomy webpage | Twitter | LinkedIn | Googlescholar | Researchgate | ORCID
Profile
I am currently a researcher at the University of Leeds, working on microfluidic platforms for ice nucleation studies. I obtained an MChem degree (2007) and a PhD (2011) in analytical chemistry from the University of Hull (UK). I then worked as a post doc at KIST Europe (Germany) from 2011-2012 on the development of detection systems for capillary electrophoresis. Prior to my position at Leeds, I was a postdoc on a project involving miniaturised quality control testing in positron emission tomography (PET) radiotracer production from 2012-2016 (University of Hull).
I now work within the Ice Nucleation Group in the Institute for Climate and Atmospheric Science (ICAS) at the University of Leeds, and jointly with the Molecular & Nanoscale Physics (MNP) Group in the Faculty of Mathematics and Physical Sciences.
- MChem Chemistry with Forensic Science and Toxicology (1st Class hon.), University of Hull, 2007
- PGDip Postgraduate Diploma in Research Training, University of Hull, 2010
- PhD Chemistry, University of Hull, 2011:
'Continuous flow processes on single magnetic and diamagnetic particles in microfluidic devices'
- Member of the Royal Society of Chemistry (MRSC)
- Member of The Aerosol Society
Development of a new microfluidics instrument to measure the concentration of atmospheric ice nucleating particles
- Professor Ben Murray
- Dr. Jung-uk Shim
'Ice Nucleating Particles in the Marine Atmosphere (MarineIce)', ERC (European Research Council), 2015-2020
Papers
- Tarn MD; Sikora SNF; Porter GCE; O'Sullivan D; Adams M; Whale TF; Harrison AD; Vergara-Temprado J; Wilson TW; Shim J-u; Murray BJ (2018) The study of atmospheric ice-nucleating particles via microfluidically generated droplets, Microfluidics and Nanofluidics, 22, pp.52. doi: 10.1007/s10404-018-2069-x
- Castro ER; Tarn MD; Ginterová P; Zhu H; Xu Y; Neužil P (2018) Determination of dynamic contact angles within microfluidic devices, Microfluidics and Nanofluidics, 22, pp.51. doi: 10.1007/s10404-018-2066-0
- Lu B; Tarn MD; Pamme N; Georgiou TK (2018) Fabrication of tailorable pH responsive cationic amphiphilic microgels on a microfluidic device for drug release, Journal of Polymer Science, Part A: Polymer Chemistry, 56, pp.59-66. doi: 10.1002/pola.28860
- Alorabi AQ; Tarn MD; Gómez-Pastora J; Bringas E; Ortiz I; Paunov VN; Pamme N (2017) On-chip polyelectrolyte coating onto magnetic droplets - Towards continuous flow assembly of drug delivery capsules, Lab on a Chip, 17, pp.3785-3795. doi: 10.1039/c7lc00918f
- Lee SJ; Castro ER; Guijt RM; Tarn MD; Manz A (2017) Van de Graaff generator for capillary electrophoresis, Journal of Chromatography A, 1517, pp.195-202. doi: 10.1016/j.chroma.2017.08.026
- Ngamsom B; Truyts A; Fourie L; Kumar S; Tarn MD; Iles A; Moodley K; Land KJ; Pamme N (2017) A microfluidic device for rapid screening of E. coli O157:H7 based on IFAST and ATP bioluminescence assay for water analysis, Chemistry - A European Journal, 23, pp.12754-12757. doi: 10.1002/chem.201703487
- Mosley O; Melling L; Tarn MD; Kemp C; Esfahani MMN; Pamme N; Shaw KJ (2016) Sample introduction interface for on-chip nucleic acid-based detection of Helicobacter pylori from stool samples, Lab on a Chip, 16, pp.2108-2115. doi: 10.1039/c6lc00228e
- Phurimsak C; Tarn MD; Pamme N (2016) Magnetic particle plug-based assays for biomarker analysis, Micromachines, 7, 77. doi: 10.3390/mi7050077
- Taggart MP; Tarn MD; Esfahani MMN; Schofield DM; Brown NJ; Archibald SJ; Deakin T; Nicole Pamme N; Thompson LF (2016) Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals, Lab on a Chip, 16, pp.1605-1616. doi: 10.1039/c6lc00099a
- Tarn MD; Maneuski D; Alexander R; Brown NJ; O’Shea V; Pimlott SL; Pamme N; Archibald SJ (2016) Positron detection in silica monoliths for miniaturised quality control of PET radiotracers, Chemical Communications, 52, pp.7221-7224. doi: 10.1039/c6cc00660d
- Esfahani MMN; Tarn MD; Choudhury TA, Hewitt LC; Mayo AJ; Rubin TA; Waller MR; Christensen MG; Dawson A; Pamme N (2016) Lab-on-a-chip workshop activities for secondary school students, Biomicrofluidics, 011301. doi: 10.1063/1.4940884
- Lu B; Tarn MD; Pamme N; Georgiou TK (2016) Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release, Journal of Materials Chemistry B, 4, pp.3086-3093. doi: 10.1039/c5tb02378e
- Tarn MD; Elders LT; Peyman SA; Pamme N (2015) Diamagnetic repulsion of particles for multilaminar flow assays, RSC Advances, 5, pp.103776-103781. doi: 10.1039/c5ra21867e
- Lu B; Tarn MD; Pamme N; Georgiou TK (2015) Tailoring pH-responsive acrylic acid microgels with hydrophobic crosslinks for drug release, Journal of Materials Chemistry B, 3, pp.4524-4529. doi: 10.1039/c5tb00222b
- Phurimsak C; Tarn MD; Peyman SA; Greenman J; Pamme N (2014) On-chip determination of C-reactive protein using magnetic particles in continuous flow, Analytical Chemistry, 86, pp.10552-10559. doi: 10.1021/ac5023265
- Phurimsak C; Yildirim E; Tarn MD; Trietsch SJ; Hankemeier T; Pamme N; Vulto P (2014) Phaseguide assisted liquid lamination for magnetic particle-based assays, Lab on a Chip, 14, pp.2334-2343. doi: 10.1039/c4lc00139g
- Tarn MD; Lopez-Martinez MJ; Pamme N (2014) REVIEW: On-chip processing of particles and cells via multilaminar flow streams, Analytical and Bioanalytical Chemistry, 406, pp.139-161. doi: 10.1007/s00216-013-7363-6
- Arima V; Pascali G; Lade O; Kretschmer HR; Bernsdorf I; Hammond V; Watts P; De Leonardis F; Tarn MD; Pamme N; Cvetkovic BZ; Dittrich PS; Vasovic N; Duane R; Jaksic A; Zacheo A; Zizzari A; Marra L; Perrone E; Salvadori PA; Rinaldi R (2013) Radiochemistry on chip: Towards dose-on-demand synthesis of PET radiopharmaceuticals, Lab on a Chip, 13, pp.2328-2336. doi: 10.1039/c3lc00055a
- Tarn MD; Peyman SA; Pamme N (2013) Simultaneous trapping of magnetic and diamagnetic particle plugs for separations and bioassays, RSC Advances, 3, pp.7209-7214. doi: 10.1039/c3ra40237a
- Tarn MD; Pascali G; De Leonardis F; Watts P; Salvadori PA; Pamme N (2013) Purification of 2-deoxy-2-[18F]fluoro-d-glucose by on-chip solid-phase extraction, Journal of Chromatography A, 1280, pp.117-121. doi: 10.1016/j.chroma.2013.01.032
- Tarn MD; Fakhrullin RF; Paunov VN; Pamme N (2013) Microfluidic device for the rapid coating of magnetic yeast cells with polyelectrolytes, Materials Letters, 95, pp.182-185. doi: 10.1016/j.matlet.2012.12.084
- Vojtíšek M; Tarn MD; Hirota N; Pamme N (2012) Microfluidic devices in superconducting magnets: On-chip free-flow diamagnetophoresis of polymer particles and bubbles, Microfluidics and Nanofluidics, 13, pp.625-635. doi: 10.1007/s10404-012-0979-6
- Tarn MD; Pamme N (2011) REVIEW: Microfluidic platforms for performing surface-based clinical assays, Expert Review of Molecular Diagnostics, 11, pp.711-720. doi: 10.1586/erm.11.59
- Rodríguez-Villarreal AI; Tarn MD; Madden LA; Lutz JB; Greenman J; Samitier J; Pamme N (2011) Flow focussing of particles and cells based on their intrinsic properties using a simple diamagnetic repulsion setup, Lab on a Chip, 11, pp.1240-1248. doi: 10.1039/c0lc00464b
- Al-Hetlani E; Hatt OJ; Vojtíšek M; Tarn MD; Iles A; Pamme N (2010) Sorting and manipulation of magnetic droplets in continuous flow, AIP Conference Proceedings, 1311, pp.167-175. doi: 10.1063/1.3530008
- Tarn MD; Peyman SA; Robert D; Iles A; Wilhelm C; Pamme N (2009) The importance of particle type selection and temperature control for on-chip free-flow magnetophoresis, Journal of Magnetism and Magnetic Materials, 321, pp.4115-4122. doi: 10.1016/j.jmmm.2009.08.016
- Tarn MD; Hirota N; Iles A; Pamme N (2009) On-chip diamagnetic repulsion in continuous flow, Science and Technology of Advanced Materials, 10, 014611. doi: 10.1088/1468-6996/10/1/014611
Book chapters
- Tarn MD; Pamme N (2017) 'On-chip magnetic particle-based immunoassays using multilaminar flow for clinical diagnostics' in Microchip Diagnostics: Methods and Protocols, Methods in Molecular Biology, vol. 1547, edited by V. Taly, J. L. Viovy and S. Descroix. Springer, New York, USA. doi: 10.1007/978-1-4939-6734-6_6
- Tarn MD; Pamme N (2013) 'Microfluidics' in Elsevier Reference Module in Chemistry, Molecular Sciences and Engineering, edited by J. Reedijk. Elsevier Inc., Waltham, MA, USA. doi: 10.1016/b978-0-12-409547-2.05351-8
Selected conference proceedings
- Tarn MD; Sikora SNF; Porter GCE; O'Sullivan D; Adams M; Whale TF; Harrison AD; Shim J-u; Murray BJ (2017) The study of atmospheric ice-nucleating particles using microfluidically generated droplets, The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah (USA), 22-26 October 2017, pp.718-719.
- Porter GCE; Tarn MD; Sikora SNF; Salter ME; Wilson TW; Whale TF; Shim J-u; Murray BJ (2017) A microfluidic platform for the study of ice-nucleating particles in remote marine environments, The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah (USA), 22-26 October 2017, pp.1429-1430.
- Tarn MD; Esfahani MMN; Chan YC; Buch JX; Onyije CC; Gawne PJ; Gambin DJB; Brown NJ; Archibald SJ; Pamme N (2017) Microanalytical devices towards integrated quality control testing of [18F]FDG radiotracer, The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah (USA), 22-26 October 2017, pp.559-560.
- Gómez-Pastora J; Alorabi AQ; Tarn MD; Bringas E; Ortiz I; Paunov VN; Pamme N (2017) Continuous generation of stable polyelectrolyte multilayer capsules inside a Snakes-and-Ladders chip, The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah (USA), 22-26 October 2017, pp.724-725.
- Al-Orabi AQ; Tarn MD; Paunov VN; Pamme N (2016) A snakes and ladders chip for the LbL assembly of polyelectrolytes on magnetic droplets, The 20th International Conference onMiniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.154-155.
- Ngamsom B; Fourie L; Tarn MD; Kumar S; Moodley K; Land K; Pamme N (2016) Rapid detection of coli O157:H7 by IFAST and ATP bioluminescence assay for water analysis, The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.63-64.
- Tarn MD; Yavuzkanat N; Esfahani MMN; Brown NJ; Pamme N; Jenkins D; Archibald SJ (2016) Plastic scintillator-based microfluidic devices for radiodetection towards the quality control testing of PET radiotracers, The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.1063-1064.
- Tarn MD; Peyman SA; Archibald SJ; Evans SD; Pamme N (2016) Simple fabrication of all-glass herringbone devices for the rapid production of liposomes, The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.1045-1046.
- Tarn MD; Peyman SA; Corlyon C; Momtazian H; Smith J; Spencer MD; Taylor SL; Lorch M; Pamme N (2016) Minecraft for microfluidics: Teaching lab-on-a-chip to younger generations, The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.1513-1514.
- Bignell HA; Tarn MD; Burke BP; Pamme N; Archibald SJ (2016) Microfluidic radiolabelling of the chelator DOTA with gallium-68 at room temperature for use in PET imaging, The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.1577-1578.
- Lu B; Tarn MD; Pamme N; Georgiou TK (2016) Microfluidic fabrication of novel pH-responsive amphiphilic microgels for drug delivery, The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.729-730.
- Mosley O; Melling L; Tarn MD; Kemp C; Esfahani MMN; Pamme N; Shaw KJ (2016) Sample introduction interface for on-chip nucleic acid-based analysis of Helicobacter pylori from stool samples, The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin (Ireland), 9-13 October 2016, pp.709-710.
- He P; Tarn MD; Esfahani MMN; Brown NJ; Pamme N; Archibald SJ (2016) Integrated microfluidic lab-on-a-chip systems for synthesis and purification of fluorine-18 radiotracers, European Journal of Nuclear Medicine and Molecular Imaging, 43 (Supplement 1), pp.S240 (EPW90). doi: 10.1007/s00259-016-3484-4
- Taggart MP; Tarn MD; Esfahani MMN; Archibald SJ; Deakin T; Pamme N; Thompson LF (2015) On-chip detection of radioactivity via silicon-based sensors for the quality control testing of radiopharmaceuticals, The 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Gyeongju (Korea), 25-29 October 2015, pp.1849-1851.
- Lu B; Tarn MD; Pamme N; Georgiou TK (2015) Novel amphiphilic microgels fabricated via on-chip polymerisation, The 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2015), Gyeongju (Korea), 25-29 October 2015, pp.1044-1046.
- Tarn MD; Brown NJ; Pamme N; Archibald SJ (2015) Integrated microfluidic radiotracer quality control: Miniaturised on-chip absorbance spectroscopy, Journal of Labelled Compounds and Radiopharmaceuticals, 58 (S1-S74), pp.S20. doi: 10.1002/jlcr.3302_1
- Archibald SJ; Pamme N; Brown NJ; Tarn MD (2015) Integrated microfluidic lab-on-a-chip systems for 18F radiotracer synthesis, purification and quality control, Journal of Nuclear Medicine, 56 (Supplement 3), pp.167.
- Tarn MD; Isu A; Archibald SJ; Pamme N (2014) On-chip absorbance spectroscopy for the determination of pH and optical clarity for the quality control testing of [18F]FDG radiotracer, The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio (USA), 26-30 October 2014, pp.1077-1079.
- Lu B; Tarn MD; Pamme N; Georgiou TK (2014) Amphiphilic microgels from polymerisation of hydrophobic droplets – Novel microgels fabricated on-chip, The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio (USA), 26-30 October 2014, pp.1199-1201.
- Al-Orabi AQ; Schofield Z; Tarn MD; Paunov VN; Pamme N (2014) On-chip assembly of polyelectrolyte capsules on magnetic templates, The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio (USA), 26-30 October 2014, pp.1238-1240.
- Castro ER; Tarn MD; Ginterová P; Neuzil P; Manz A (2014) Single point detection method for surface characterization of channels in microfluidic chips, The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), San Antonio (USA), 26-30 October 2014, pp.1650-1652.
- Lu B; Tarn MD; Georgiou TK; Pamme N (2014) Novel microgels fabricated on microfluidic devices, 4th Micro and Nano Flows Conference (MNF 14), Uxbridge (UK), 7-10 September 2014.
- Phurimask C; Yildirim E; Trietsch SJ; Hankemeier T; Tarn MD; Pamme N; Vulto P (2013) Phaseguide assisted liquid lamination for magnetic bead-based assays, The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013), Freiburg (Germany), 27-31 October 2013, pp.1153-1155.
- Tarn MD; Lu B; Smith R; Burke BP; Archibald SJ; Pamme N (2013) Copper complexation of macrocyclic molecules: Towards on-chip radiometallic labelling of PET radiotracers, The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013), Freiburg (Germany), 27-31 October 2013, pp.1890-1892.
- Tarn MD; Pascali G; De Leonardis F; Watts P; Salvadori PA; Pamme N (2012) On-chip purification of [18F]FDG in Positron Emission Tomography radiotracer synthesis, The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2012), Okinawa (Japan), 28 October - 1 November 2012, pp.1795-1797.
- Tarn MD; Peyman SA; Rodríguez-Villarreal AI; Swinley A; Pamme N (2011) Trapping and focusing of particles and cells based on magnetic attraction and diamagnetic repulsion, The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2011), Seattle (USA), 2-6 October 2011, pp.632-634.
- Vojtíšek M; Tarn MD; Hirota N; Pamme N (2011) Lab-on-a-chip in superconducting magnets – A tool for particle separations and bubble manipulation via diamagnetic repulsion, The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2011), Seattle (USA), 2-6 October 2011, pp.1335-1337.
- De Leonardis F; Tarn MD; Pascali G; Salvadori PA; Pamme N (2011) Microfluidic modules for the preconcentration of [18F]-fluoride for PET radiotracer synthesis, and its subsequent removal during product purification, Journal of Labelled Compounds and Radiopharmaceuticals, 54 (S1-S89), pp.S46. doi: 10.1002/jlcr.1925
- Tarn MD; Peyman SA; Fakhrullin RF; Iles A; Paunov VN; Pamme N (2010) Magnetically-actuated particle-based procedures in continuous flow, The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2010), Groningen (The Netherlands), 3-7 October 2010, pp.1679-1681.
- Al-Hetlani E; Hatt OJ; Vojtíšek M; Tarn MD; Pamme N (2010) Magnetic droplets – Generation and manipulation in continuous flow, The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2010), Groningen (The Netherlands), 3-7 October 2010, pp.1817-1819.
- Vojtíšek M; Tarn MD; Iles A; Pamme N (2009) Rapid and continuous on-chip multistep chemical processing on magnetic particles, The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2009), Jeju (Korea), 1-5 November 2009, pp.1497-1499.
- Peyman SA; Kwan E-Y; Margarson O; Tarn MD; Iles A; Pamme N (2009) Diamagnetic repulsion – A versatile means for the manipulation of objects in microfluidic devices, The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2009), Jeju (Korea), 1-5 November 2009, pp.1458-1460.
- Tarn MD; Robert D; Peyman SA; Iles A; Wilhelm C; Pamme N (2009) Temperature-based tuning of magnetic particle separations, The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2009), Jeju (Korea), 1-5 November 2009, pp.1449-1451.
- Tarn MD; Peyman SA; Vojtíšek M; Iles A; Pamme N (2009) The generation of multi-laminar reagent streams for rapid, sequential (bio)chemical reactions on magnetic particles in a continuous flow microreactor, 2nd Micro and Nano Flows Conference (MNF 09), Uxbridge (UK), 1-2 September 2009.
- Tarn MD; Robert D; Peyman SA; Iles A; Wilhelm C; Pamme N (2009) Temperature-based tuning of magnetic particle separation by on-chip free-flow magnetophoresis, 2nd Micro and Nano Flows Conference (MNF 09), Uxbridge (UK), 1-2 September 2009.
Patent applications
- Archibald SJ; He P; Haswell SJ; Pamme N; Brown NJ; Tarn MD; Alexander R (2016) Radioisotope recovery, Publication no.: WO2016063069 A1, Filing date: 22 October 2015, Publication date: 28 April 2016.
- Archibald SJ; He P; Haswell SJ; Pamme N; Brown NJ; Tarn MD; Alexander R; Esfahani MMN (2016) Method and apparatus for the analysis of compounds, Publication no.: WO2016063068 A2, Filing date: 22 October 2015, Publication date: 28 April 2016.
- Archibald SJ; He P; Haswell SJ; Pamme N; Brown NJ; Tarn MD; Alexander R; Esfahani MMN (2016) Monolithic body, Publication no.: WO2016063070 A1, Filing date: 22 October 2015, Publication date: 28 April 2016.
- Archibald SJ; He P; Haswell SJ; Pamme N; Brown NJ; Tarn MD; Alexander R; Esfahani MMN (2016) System for radiopharmaceutical production, Publication no.: WO2016063072 A1, Filing date: 22 October 2015, Publication date: 28 April 2016.
Qualifications
- PhD Chemistry
- MChem Chemistry with Forensic Science and Toxicology (1st Class)
- PGDip in Research Training
Professional memberships
- Royal Society of Chemistry (MRSC)
Research groups and institutes
- Institute for Climate and Atmospheric Science